The only problem that I've encountered with Clik valves is that the ones I have don't always fit every Presta valve stem. I just bought some aluminum alloy valve stems, and the Clik valve won't screw into them, whilst the Presta valve cores do. I attribute this to companies manufacturing stems with varying tolerances and therefore machining their stems to fit Presta cores. Conversely, it could be that the Clik valves I have are out of tolerance. The Clik valves that do fit the stems I've tried are mostly brass (some DT Swiss) and one aluminum-on-aluminum pair that came with an Elitewheels wheelset. The Presta valves are a bit loose, but they still work fine. I have also noticed that due to poor standardization of the internal thread length, the Clik valve is not always tightened all the way to the shoulder (while the Presta has no shoulder) and sometimes the thread in the shank is too long, so that the Clik valve shoulder prevents a complete seal.
Apparently... "The inner thread length (engagement depth) of a Presta valve stem is not a universally published, precise standard measurement like diameter and pitch. This is because the inner depth can vary slightly between manufacturers and stem lengths, but all are designed to securely accept a standardized Presta valve core."
The thread of the Presta core tip is designated as 5V2 according to the ISO 4570 standard and measures 5.2 mm diameter x 1.058 mm pitch, and I assume that must be the same for the Clik valve.
I contacted Clik Valve about this, but received no response, so it must be a problem they're aware of but don't want to address. Overall, I'm very happy with their performance and hope they become more widespread, but if you have aluminum alloy valve stems, you might not be able to use the CVs due to the inconsistent thread interfaces.
Update 2026/01/25:
I bought two Schwalbe Clik valves with 40mm stems, and both valves fit all my Presta stems, including the aluminum alloy stem shown in the photo. I installed this stem on an Airshot (like the Schwalbe Tyre Booster) to replace the combined Presta stem and valve.
The Schwalbe stems have both a maximum-sized hole through the stem and three holes at the base. The fitting accepts a 4mm Allen key for tightening. This is as good as it gets for maximizing air and sealant flow through a Presta shank. This isn't clearly shown or stated in their advertising.
I can only conclude that I had a few Clik valves with poor thread quality, and this could be supported by Clik's statement in an email that they had improved the machining.